The Natural Thyroid Diet

Thyroid Factor

Thyroid Factor is a program that was created by Dawn Sylvester to help women deal with thyroid issues. Dawn Sylvester is a 57 years old lady that has worked with 1,000's of real women. She has over the time tried to investigate the underlying reason why majority of women lose energy and also struggle with belly fat and fatigue as they age. It is a comprehensive program thatcomprises of Thyro pause, 11 kinds of thyroid saving foods that will work to help you boost fat burning Free T3. The program also teaches you all the hidden causes of thyroid which are making you fat and later a highly reliable Thyroid reboot plan which is an excellent plan you need to tackle your weight. Additionally, there are tips to reduce bulging fat fast and eventually obtain a healthy body. You also get several bonuses all aimed at helping you solve all the problems that comes with being overweight. The three bonuses you get are 21 Day Thyroid weight loss system, 101 Thyroid boosting foods and Thyroid Jumpstart Guide. Read more...

Thyroid Factor Summary


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Thyroid hormone T to the higheractivity T

Cause a decrease in thyroid activity. Thyro Stak, unlike the pharmaceutical preparations Synthroid and Cytomel, is not a source of active thyroid hormone. That's an important distinction. Thyro Stak will allow your body to maintain a degree of regulation, rather than subjecting it to whatever dose people assault their bodies with in an attempt to meet weight-loss or bodyshaping goals. Guggulsterones have been shown to stimulate the thyroid gland to release thyroid hormone. Phosphates have been shown to increase the rate of conversion of the low-activity thyroid hormone, T4, to the higher-activity T3. If you have a normal thyroid function, your body keeps your thyroid at a normal level when it's in a well-fed and rested state. When you subject yourself to stress, thyroid function and activity drop, giving you that sluggish state in which you have no energy, and fat loss grinds to a standstill. That stress may come from dropping calories below maintenance, dropping carbs, using...

Thyroid Medication

Many bodybuilders trying to lose weight are indiscriminate in their use of thyroid medication. They little realize that an over-stimulated thyroid gland causes a loss of muscle tissue at the same rate as fat. Because this gland controls the speed of all cellular processes, it is not selective in banishing fat rather than muscle for the convenience of bodybuilders. In addition, thyroid medication has the harmful effect of also stimulating the parathyroid gland, controlling the calcium content of the bones When stimulated,the parathyroid draws calcium from the bones into the blood tissue. Remember, a calcium deficiency can lead to muscle spasms and cramps during training and a decrease in performance. The hyperactivity most often associated with taking thyroid drugs is not the hallmark of a champion.

What Causes Free Radicals

Another way our metabolism is increased is by overactivity of the thyroid. Normally, the thyroid gland hormones regulate our metabolism. Overproduction increases metabolism (hyperthyroidism) and underproduction (hypothyroidism) slows metabolism. Persons suffering from hyperthyroidism require a greater supply of antioxidants to protect themselves against this increase in free-radical production. Medical practitioners rarely take this into consideration. It was observed many years ago that underfeeding lengthens the life spans of several species of lower animals. This finding has been reproduced in scientific studies several times since then. At least two highly respected scientists maintain a very low food intake in an effort to increase their longevity. While no one has specifically connected free-radical generation to the phenomenon of aging, it is obvious that one of the effects of underfeeding is a reduction in the production of thyroid hormones and a slowing of metabolism. It is...

A General considerations

Standards are now rarely given in the breeder management guides. It is known that most (90 ) of the frame size is developed early, and so by 1216 weeks of age, the so-called 'size' of the pullet is fixed. While this parameter is useful as another monitoring tool, we have had little success in affecting frame size without also affecting body weight. It therefore seems very difficult to produce, by nutritional modification, pullets that are below target weight, yet above average frame size and vice versa. Since shank length and 'frame size' are so highly correlated with body weight, their measurement or monitoring is no longer considered necessary. However, an exception to this rule occurs in hot weather conditions where high temperatures seem to stimulate leg bone growth independent of body weight. It is not clear why birds held at higher temperatures have longer shank bones, although there is a possibility of altered hormone balance. For example, thyroid hormones are known to...

Fetal growth factors and fetal nutrition

Thyroid hormones are also involved in regulating fetal metabolism and thus growth. The metabolic action of thyroxine is mainly via stimulation of oxygen utilizationby fetal tissues.213 This appears to be a general increase in oxidative metabolism, rather than in glucose oxidation alone.76 Thyroid hormones are reduced, and thyroid stimulating hor

Other minerals iodine and selenium

The non-metallic element iodine is an essential nutrient that, apparently, has a single function in the body as a component of the thyroid hormones thyroxine (T4) and triiodotyronine (T3). These hormones are necessary for a range of body processes, the most important of which are the control of metabolic rate, cellular metabolism, growth and neural development. Production of T4 and T3 is controlled by tissue demands which are mediated by the secretions of the pituitary gland and by the supply of iodine in the diet. Deficiency of iodine can result in a number of diseases, ranging from severe cretinism with mental retardation to barely visible enlargement of the thyroid gland. Goitre is the name given to enlargement of the gland that occurs as the body attempts to compensate for a reduction of its supply of iodine by increasing the size of the gland. The amount of enlargement is related to the degree of iodine deficiency. The condition is widespread throughout the world, with up to a...

Have You Ever Wondered 112

. . . if high blood cholesterol could be linked to a thyroid problem Yes, it could. Hypothyroidism-when the thyroid gland doesn't produce enough of the hormone thyroxin-has many symptoms. Among them are a sluggish feeling, poor memory, dry skin and hair, feeling cold, constipation, heavy menstrual flow, weight gain, and muscle cramps. Elevated LDL cholesterol may be another and serious side effect. Treating hypothyroidism with medication-thyroid hormone-also helps reduce high LDL cholesterol levels associated with this condition. Untreated, hypo-thyroidism can damage the cardiovascular system permanently. As part of a routine physical exam, have your physician check for thyroid problems. Hypothyroidism is much more common among women than among men.

Have You Ever Wondered

. . . if my weight problem is really a thyroid problem Maybe-but before you blame your thyroid, check with your doctor, who may order a test to find out. Hypothyroidism, when the thyroid doesn't produce enough thyroid hormone, is the most common form of thyroid disease one symptom is weight gain. On the flip side, an overactive thyroid causes hyperthyroidism one symptom is weight loss. See chapter22, page 551, with a Have You Ever Wondered question about thyroid disease and high blood cholesterol.

Use in Prevention and Therapy

Ample intake of iodine (from seafood, iodized salt, or kelp supplements), especially during pregnancy, lactation, and childhood, will maintain production of thyroid hormone and prevent IDD. Inadequate iodine intake during childhood can impair learning ability and school performance.2 Hypothyroidism. If the iodine content of the diet is marginal or low, borderline hypothy-roidism may produce symptoms of fatigue, lassitude, and poor concentration. Replenishing thyroid stores of iodine can be beneficial.

Central Nervous System Localization Of Feeding Control

The hypothalamus integrates diverse signals, including brain neurotransmitters, peripheral neurohumoral afferents, adipocyte-derived signals, gastrointestinal peptides, and other afferent inputs, to regulate energy homeostasis. The arcuate nucleus (ARC) at the base of the hypothalamus expresses receptors for hormones and neuropeptides that regulate feeding. The paraventricular nucleus (PVN) in the anterior hypothalamus, the major site of corticotropin releasing hormone (CRH) and Thyroid Releasing Hormone (TRH) secretion, receives rich projections from the ARC. Thus, the PVN integrates diverse paracrine and endocrine metabolic signals with classical neuroendocrine pathways mediated through the thyroid and hypotha-lamic-pituitary-adrenal axes.

Are There Different Classes of Hormones

Hormones may be grouped into one of two general categories amino acid-based hormones and steroid hormones. The amino acid-based hormones include hormones that are proteins and those hormones that are derived from the amino acid tyrosine. Examples of protein hormones include insulin, growth hormone (GH), glucagon, and antidiuretic hormone (ADH). Examples of hormones made from the amino acid tyrosine are epinephrine (adrenaline) and thyroid hormone (T3 and T4). Steroid hormones are made from cholesterol and include testosterone, estrogens, cortisol, progesterone, and aldosterone.

Joan Mother Of Maria One Of Dr Helen Schleagles Patients

My daughter has been helped in a dramatic way by alternative medical approaches. A couple of months ago, my daughter, Maria, became wildly out of control. She's only nine years old, but she was going out at five and six o'clock in the morning to shop with homeless people. She would go into violent rages and would sleep only about four or five hours a night. Finally, I couldn't keep her home any more and so I put her into a psychiatric hospital where they determined that she was suffering from manic depression. They started her on lithium but she wasn't herself she wasn't conversational the way she usually is, and she was still depressed. She had elevated liver and enzymes which, at the hospital, they failed to follow up on. She also had elevated levels of thyroid hormone, which they also failed to follow up on. After three weeks in the hospital, she had calmed down somewhat, and I was able to take her home. She still wasn't well. I had been consulting with Dr. Schleagle while Maria...

AS expression and cell cycle control

By sequence homology, the human clone was identified as AS and confirmed by the ability ofexogenously added asparagine to bypass the tsll mutation. When grown at the non-permissive temperature, the BHK tsll cells produce an inactive asparagine synthetase (Gong and Basilico, 1990), resulting in depletion of cellular asparagine and a corresponding increase in AS mRNA. The addition of asparagine to the medium led to a decrease in AS mRNA levels (Greco et al., 1989). Also showing a link between asparagine content and the cell cycle, AS mRNA was increased substantially by refeeding serum to serum-deprived Balb c 3T3 cells (Greco et al, 1987). The AS mRNA was induced at approximately mid-G1 phase in human, mouse and hamster cells, and the addition of asparagine to the culture medium prevented the G1 induction in serum-stimulated cells. Hongo et al. (1989) showed that AS activity is induced during lymphocyte activation by phytohaemag-glutinin, and the increase...

How Much Body Protein Would We Lose During Fasting

Amazingly, our brain can replace about half of its glucose requirement with ketone bodies after a week or so of complete starvation. Second, during prolonged energy restriction, the thyroid gland may release less and less thyroid hormone. This slows our RMR and in turn decreases the requirement for protein breakdown.

Reducing Elevated Cholesterol or Triglycerides

Clinical trials have shown it to be generally safe. Some will have gastric upset, headache, mild nausea and hiccups. It also can stimulate thyroid activity and should be used with caution when taking thyroid medications. It is contraindicated for those with hyperthyroidism. Interactions with other medications. It can interfere with the effectiveness of propranolol (Inderal) and diltiazem (Cardizem) and may interfere with thyroid therapies. (Natural Medicines Comprehensive Database, 2001)

Mechanism Of Vitamin A Action

RA and its isomer, 9-ds-retinoic acid (9cRA), serve as ligands that activate ligand-activated transcription factors that belong to a superfamily of nuclear receptors.10 This superfamily of related genes expresses nuclear receptors for steroids (the female sex hormones estrogen and progesterone, the mineralocorticoid aldoster-one, the glucocorticoid cortisol, the male sex hormones testosterone and dihy-drotestosterone), prostanoids, the thyroid hormone, the hormonal form of vitamin D, calcitriol, and peroxisome proliferators. Additionally, more than 50 orphan receptors belong to this family. Two classes of retinoid receptors occur retinoic acid receptors (RAR) and retinoid X receptors (RXR). Each has three different versions (a, p, and y) encoded by distinct genes. Each version also has multiple isoforms resulting from differential promoter use and alternative RNA splicing. Thus, multiple forms of each occur (e.g., RARa1, RARa2, etc.). Moreover, RAR functions as a heterodimer with RXR....

Anticarcinogenic Activity Of Vitamin A Retinoids And Rexinoids

The RXRs form stable heterodimers with RARs. They also can form homodimers and are capable of acting independently from RARs. Furthermore, RXRs also form heterodimers with the vitamin D receptor, the thyroid hormone receptors, and peroxisome proliferation-activating receptors. In this context, specific analogs for RXRs, which are now called rexinoids, are of particular interest for application to the field of control and regulation for various diseases and biological phenomena, including cancer control.

Dietary components and health

The availability of food in Europe has never been as good as in recent decades. Affluent though European countries are, sub-groups of populations experience the deficiency of minerals and micronutrients that play a vital role in health and development (Serra-Majem, 2001). A significant proportion of European infants and children are today experiencing a low dietary intake of iodine and iron (Trichopoulou and Lagiou, 1997a WHO, 1998). The iodine deficiency leads to several disorders collectively referred to as Iodine Deficiency Disorders (IDD), with goitre (hyperplasia of thyroid cells), cretinism (mental deficiency) and severe brain damage being the most common. It is estimated that IDD may affect approximately 16 of the European population. Furthermore, inadequate levels of folate have been implicated with a rise in the blood homocysteine levels, leading possibly to increased risk of cardiovascular disease (CVD). European policies address such deficiencies either by recommending the...

Taking offense to tastes

People with this gene can taste very small concentrations of a chemical called phenylthiocarbamide (PTC). Because PTC is potentially toxic, Dr. Bartoshuk tests for the trait by having people taste a piece of paper impregnated with 6-n-propylthiouracil, a thyroid medication whose flavor and chemical structure are similar to PTC. People who say the paper tastes bitter are called PTC tasters. People who taste only paper are called PTC nontasters.

Etiology of Low Bone Mass in Athletes

Disordered eating, present with low BMD in the absence of menstrual dysfunction 74,78 . Studies aimed at correcting the hypoestrogenic state, using estra-diol replacement (without an increase in energy intake), generally have not succeeded in the normalization of BMD after years of treatment 81-84 , indicating that factors other than estrogen also are important for bone. The most convincing evidence that low energy availability may have a direct effect on bone was published in an article by Ihle and Loucks 85 , who showed that markers of bone formation and resorption changed unfavorably within 5 days in sedentary women who were exposed to low energy availability through dietary restriction or increased exercise energy expenditure 85 . Whether this is also the case in athletic women has yet to be determined. Nevertheless, it seems highly plausible that an energy and nutrient deficit affects metabolic substrates and hormones, including insulin, growth hormone, insulin-like growth...

Other Additives to Avoid Aspartame Nutra Sweet Equal

This particularly nasty substance should have never even been approved for human use. In fact, had it not been for some fancy footwork by those in power in the FDA, it never would have. Early experiments using low, medium, and high doses with aspartame all found dramatic tumor increases in test animals. These included brain, pancreas, and breast tumors, and tumors of the testes, thyroid, and prostate. Experiments also demonstrated a direct correlation between intake quantity and tumor incidence.

Evidence that MVMM Supplementation during Pregnancy is Beneficial

ANote that this supplement formulation was suggested prior to the establishment of (1) the DRI values, (2) the American Thyroid Association recommendation that all pregnant women receive iodine supplements (150 mcg day), and (3) the current recommendation that all women of childbearing age consume 0.4 mg day (400mcg day) folic acid in the form of supplements or fortified foods aNote that this supplement formulation was suggested prior to the establishment of (1) the DRI values, (2) the American Thyroid Association recommendation that all pregnant women receive iodine supplements (150 mcg day), and (3) the current recommendation that all women of childbearing age consume 0.4 mg day (400mcg day) folic acid in the form of supplements or fortified foods

Mary Frances Picciano and Michelle Kay McGuire

Summary National surveys indicate that as many as 97 of women living in the United States are advised by their health care providers to take multivitamin, multimineral (MVMM) supplements during pregnancy, and 7-36 of pregnant women use botanical supplements during this time. Although there is evidence of benefit from some of these preparations, efficacy has not been established for most of them. This chapter reviews some of the most commonly used prenatal supplements in terms of the evidence for their need, efficacy, and safety. Specifically, MVMM, folate, vitamin B6, vitamin A, vitamin D, iron, zinc, magnesium, and iodine are discussed, as are several botanicals. Data indicate that, in general, evidence for benefit gained from taking prenatal MVMM supplements is not well established except for women who smoke, abuse alcohol or drugs, are anemic, or have poor quality diets. Because of folate's well-established effect on decreasing risk for neural tube defects, it is recommended that...

Vitamin C Ascorbic Acid

Vitamin C is needed to form and maintain collagen, a fibrous protein that gives strength to connective tissues in skin, cartilage, bones, teeth, and joints. Collagen is also needed for the healing of wounds. When added to meals, vitamin C increases intestinal absorption of iron from plant-based foods. High concentration of vitamin C in white blood cells enables the immune system to function properly by providing protection against oxidative damage from free radicals generated during their action against bacterial, viral, or fungal infections. Vitamin C also recycles oxidized vitamin E for reuse in cells, and it helps folic acid convert to its active form, (THF). Vitamin C helps synthesize carnitine, adrenaline, epinephrine, the neurotransmitter serotonin, the thyroid hormone thyroxine, bile acids, and steroid hormones.

Impact on health absorption and recommended intakes

In organic combinations as physiologically important compounds, e.g. phosphorus in nucelotides, zinc in enzymes such as carbonic anhydrase, iodine in thyroid hormone. If an essential element is at a low level in the diet, a nutritional deficiency may occur, with specific symptoms. Thus an inadequate intake of iron can cause anaemia when there is insufficient haemoglobin to meet the needs of the body for oxygen transport. A deficiency of iodine can lead to goitre when the body tries to compensate for a low production of the iodine-containing thyroid hormone by increasing the size of the thyroid gland. Inadequate zinc may result in growth failure in children. Usually these conditions are corrected when intake of the missing element is increased by improving the diet or by providing supplements.

Regulation of Gene Expression

Of the all-trans- to the 9-cis form favors RXR-mediated effects of RA. To date, more than 30 different nuclear receptors for retinoids have been identified. The actual RAR RXR effect on gene expression requires the binding of RXR (including its ligand-cis-RA) to another receptor (heterodimerization) (E). This receptor can be an RA, thyroid, vitamin D, estrogen, androgen, or progesterone receptor. Different types of heterodimerization can result in different forms of binding to DNA resulting in different gene expression. The retin-oid receptor works as a transcription factor, increasing transcription in proportion to the amount of RA present. RA has an inhibitory effect on other transcription factors like AP-1 (activation protein 1), which enhances gene expression of various proteins. It is thought that this occurs through heterodimerization of RAR and or RXR with the subunits of AP-1, fos, and jun, which are proto-oncogenes. Since receptors for growth hormone, onco-genes,...

Mercury Exposure in Adulthood

In a German study of women who had repeated miscarriages, a direct correlation was found between the load of mercury in the tissues and the number of miscarriages.62 In this study 111 women with repeated miscarriages were examined for heavy metal toxicity as well as detailed hormone (progesterone, estrogen, prolactin, and thyroid stimulating hormone) and immunological studies (natural killer cells and T-cell subpopulations). It was proposed from the findings that mercury alters the mother's immunity to such an extent that it interferes with normal immunological tolerance seen during a normal pregnancy. When a woman becomes pregnant the baby exists within her as if it were part of her own tissues. The mother's immune system is thus altered to prevent her body from automatically rejecting this new entity. This condition is known as immunological tolerance mercury appears to significantly alter this process.

Key Aspects Of Energy Expenditure

Another term to describe basal levels of energy expenditure is basal metabolic rate (BMR). While at the Mayo Clinic, Dr Boothby defined and popularized use of the BMR for the diagnosis of thyroid disorders. He defined this function as the energy expended by an individual bodily and mentally at rest in a thermoneutral environment 12 to 18 hours after a meal. Much to the inconvenience of the patient, measurements were done during the early morning hours when, in addition, the circadian rhythm of oxygen consumption was known to be low. Because of the increase in metabolism caused by the muscular and mental unrest introduced by this procedure, it is unlikely that the true basal metabolism was often measured. Therefore, for practical and conceptual reasons, the BMR is now rarely measured. In its place, we now measure what is referred to as the resting metabolic rate (or resting energy expenditure), which may be (but is not always) higher than the BMR. The RMR is primarily related to the...

Poison Toxin Sources

Acute fluoride poisoning Abdominal pain, diarrhea, vomiting, excessive salivation, thirst, perspiration, and painful spasms of the limbs Chronic fluoride poisoning Abnormal teeth (especially mottled enamel) during the first 8 years of life and brittle bones. Other effects, predicted from animal studies, may include loss of body weight and altered structure and function of the thyroid gland and kidneys Water containing 3 to 10 ppm of fluoride may cause mottling of the teeth

Weight Loss Drugs and Supplements

The mainstream use of prescription drugs for weight loss extends back to the start of the 20th century. Since then several drugs including thyroid hormone and more recently phen-fen have been offered to patients to help shed those unwanted pounds. Today only a few options are available for weight loss and the mode of action is either appetite suppression or lipase inhibition.

Vital Protein Functions

Amino acids are the basic components of hormones, which are essential chemical signaling messengers of the body. Hormones are secreted into the bloodstream by endocrine glands, such as the thyroid gland, adrenal glands, pancreas, and other ductless glands, and regulate bodily functions and processes. For example, the hormone insulin, secreted by the pancreas, works to lower the blood glucose level after meals. Insulin is made up of forty-eight amino acids.

Fruits And Vegetables A Population Studies

Different fruits and vegetables have been investigated separately and appear to provide protection against cancer at certain locations. For example, the use of carrots and green, leafy vegetables provides substantial protection against lung and stomach cancers, while the cruciferous vegetables (cabbage, broccoli, cauliflower, etc.) provide useful protection against colorectal and thyroid cancers. In addition, the regular use of onions or garlic can decrease the risk of stomach and colon cancer by 50-60 ,3,10,11 while the regular consumption of tomatoes and strawberries was recently found to substantially protect against prostate cancer.12

Legumes Containing the Factors

It seems that cabbage goitrogens inhibit iodine uptake by directly affecting the thyroid gland. Cabbage goiter can be treated by iodine supplementation. Brassica seed goiter can result from the consumption of the seeds of brassica plants (e.g., rutabaga, turnip, cabbage, and rape), which contain goitrogens that prevent thyroxine synthesis. This type of goiter can only be treated by administration of the thyroid hormone. Legume goiter is induced by goitrogens in legumes such as soybeans and peanuts. It differs from cabbage goiter in that the thyroid gland does not lose its activity for iodine. Inhibition of the intestinal absorption of iodine or the reabsorption of thyroxine has been shown in this case. Legume goiter can be treated by iodine therapy. Glucosinolates, which have been shown to induce goiter, at least in experimental animals, are found in several foods and feedstuffs broccoli (buds), brussels sprouts (head), cabbage (head), cauliflower (buds), garden cress...

Klaus KA Witte and Andrew L Clark

Relationship Between Vit And Copper

The most common cause of micronutrient deficiency is a consequence of reduced dietary intake and the role of a particular micronutrient is often uncovered when the consequences of dietary deficiencies such as selenium deficiency (Keshan disease) in China and iodine deficiency (thyroid disease) in the U.K. manifest themselves. (Table 6.1 provides a summary of particular micronutrient deficiencies and their possible contribution to cardiovascular disease.) However, micronutrient deficiency in cardiovascular disease could also be a product of increased losses resulting from the condition, medical therapy, or increased requirements, for example, due to greater levels of oxidative stress. Acute supplementation of individual agents in patients with established coronary disease or at high risk of future events has generally been unsuccessful in randomised trials. This chapter reviews the potential cardiovascular benefits of individual micronutrient supplementation using animal and in vitro...

Is Being Overweight and Obese Due to Genetic Reasons

An argument can easily be made that nearly all aspects of our being have a genetic basis. Thus genetic disposition must be involved in determining body weight and composition. But how Although faulty genes can certainly play a role in establishing a sluggish metabolism in some people, scientists estimate that this may account for only a small percentage of obese individuals. Here the problem may lie in hormonal imbalances, such as lowered thyroid hormone. Scientists also believe that some people are genetically inclined to store body fat and hold on to it once it is stored. In this situation the cause is not hormonal as much as altered activity of the enzymes and other factors involved in storing fat.

Other Effects of Fluoride

Fluoride and the Thyroid Because of the problem of fluoride accumulation in our environment, serious multiple organ disorders are likely to begin occurring soon throughout the population. For instance, there is compelling evidence that the thyroid accumulates fluoride from the environment. In a study of fluoride concentrations in various human organs, Yiamouyiannis reported that the thyroid gland contained 4 ppm of fluoride after prolonged exposure.144 Also, in a chart in which he compares thyroid fluoride concentrations of human body tissues before and after water fluoridation programs were instituted in the 1940s, he found that no organ contained more than 0.68 ppm fluoride before 1940. This change represents a drastic accumulation of this toxic substance in our population, caused purely by the fluoridation program. Further, only the kidney, at 2.3 ppm, came anywhere close to the thyroid gland in its ability to accumulate fluoride. According to the USPHS, we are now approaching...

Helen A Patient Of Dr Helen Schleagle

Then I moved to California and I had heard, previous to my moving, about Dr. Schleagle and her work with depression. In fact, I referred friends to her, friends I had made in California, and they had these miraculous cures from depression after two weeks of taking B-complex and amino acids. But I didn't think of going to her myself for quite awhile because I thought of her as someone who only treated depression. In fact, like many alternative physicians, she treats the whole person. She had worked with fatigue a lot, and she first tested me thoroughly and found that my thyroid and, in fact, my whole endocrine system, was not functioning properly--most likely as a result of prednisone. She picked up subtleties in the test that other doctors ignored. She has the philosophy that a body should be healthy and whole. She doesn't need gross parameters of unusual test results to say something is wrong here. So she was able to discover that I had a rather unusual problem in my thyroid and she...

Jenny A Patient Of Dr Spreen

Spreen put me on very low doses of thyroid and immediately--within two to three weeks--all the problems I just mentioned were gone. Now I had had thyroid checks three times during the whole time when I was being treated for infertility, and the blood tests had always come up negative. But I knew that in my family there were thyroid problems. There are at least six members of my family that I can think of who have thyroid disorders, but mine just never showed up on my tests. After taking these very low doses of thyroid, my skin problem cleared up, I stopped biting my nails, and my legs stopped aching. The mild depression I was still I feel rather fed up with the original doctors I went to see. They treated me like I was an hysterical woman who needed to get a grip on things. I have never told them about my recovery using alternative methods because I don't think they'd be receptive to it. I did tell my therapist who has been very receptive to these new treatments...

Biochemistry And Bioavailability Of Carvocrol

Prevention, dietary guidelines for, 399-401 prostate, 67, 72, 76-77, 346 risk, dietary fiber and, 81 stomach, 65, 75, 334 thyroid, 335 uterine, 65 whole grains and, 82 Cancer risk, vegetarian diets and, 55-90 analysis interpretation, 74-78 components of vegetarian diets that may be associated with altered cancer risk, 79-85

Postprandial Lipid Distribution

Postprandial Lipid Metabolism

With other lipoproteins, it can be considered a key substance in the complex lipid transport system. During the early absorption phase, levels of enzymes involved in fat storage rise. These are mainly acetyl-CoA car-boxylase, fatty acid synthase, the malate enzymes, and a series of pentose phosphate cycle enzymes. Extracellular lipoprotein lipase activity in fatty tissues increases as well, which is necessary for fatty acid uptake from VLDL coming from the liver. At the same time, the activity of hormone-sensitive lipase, catalyzing the release of fatty acids from adipocytes, is reduced. All these events are subject to hormonal control (insulin and thyroid hormones), regulating necessary enzyme levels by up- or down-regulating transcription and translation.

Food Pyramids Obesity And Diabetes

Diabetes Biology

There are many reasons why people may become obese. A small number of people are genetically programmed to convert nutrients to fat, no matter what. These people probably eat less than normal and still gain weight. Another group of people cannot control their eating, sometimes consuming 20,000 calories at one meal. Even fewer people have a very low metabolic rate because of thyroid problems and cannot metabolize nutrients properly.

Measuring Nutrigenomic Factors

A number of studies looking at BIA of individuals from young to older ages have shown a general trend toward lower fat-free mass after the age of 50 years.23 A recent study used BIA to assess body composition of 995 acutely or chronically ill patients at hospital admission and found that the fat-free mass was significantly lower, and fat mass significantly higher in the patients, as compared to 995 healthy age and height matched controls.24 A study comparing 131 patients on chronic hemodialysis with 272 age and sex matched healthy controls found that a change in phase angle was the strongest predictor of poor prognosis in the hemodialysis patients. It seemed to be a reliable detector of clinically overt depletion of lean body mass and changes in intracellular electrolyte and fluid bal-ances.25 Another study demonstrated that patients with both overt and subclinical thyroid disease had altered phase angle and bioimpedance values. This study suggests that it may be a useful tool in the...

Spartan Diet Principle on Supplements

These supply iodine and other trace elements found in seafoods and sea plants (and sea salt). One of my friends on this diet hates seafood so he takes a couple of these a day to boost his intake. Failing to get enough iodine can cause your thyroid to function ab-normally and this will stuff up your metabolism.

Major Minerals Include Calcium Phosphorus and Electrolytes

PTH is released into circulation from the parathyroid gland when blood calcium levels begin to decline. PTH increases the activation of vitamin D in the kidneys and, along with vitamin D, PTH decreases the loss of calcium in urine. Vitamin D and PTH also increase the release of calcium from bone into the blood as well as increase the efficiency of calcium absorption from the small intestine. The net result is an increase in the level of calcium in the blood, thus returning it to normal (8.8 to 10.8 milligrams 100 milliliters of blood). On the contrary, the level of the hormone calcitonin in the blood increases when calcium levels increase above the normal range. Calcitonin is made by the thyroid gland and generally works opposite to PTH and vitamin D. Calcitonin decreases bone release of calcium and with the help of urinary loss of calcium promotes a reduction in blood calcium, thus returning it to the more optimal range.

William A Patient Of Dr Alan Spreen

Tyrosine is also related to the thyroid because one of the products the thyroid needs for normal functioning is tyrosine. He also put me on a low dosage of thyroid, a quarter grain a day. I took that and noticed immediate results. With that and the tyrosine, I felt like a new person.

Protein Differences Between Omnivores And Vegetarians Or Vegans

Increased thyroid activity is evident from the higher resting metabolic rate of vegans32 and of the elevated thyrotropin levels in vegans.33 This serves to explain why vegans are, on the average, leaner with lower body mass indexes (BMI).32 Also, the immune status in vegans is elevated compared with omnivore subjects in terms of significantly elevated cytokine 2 and gamma interferon levels.34

Endocrine Effects of MSG

Numerous studies using immature mice have shown that LH, FSH and prolactin (the reproductive hormones), HGH (growth hormone), ACTH (adrenal regulating hormone), and TSH (thyroid regulating hormone) were all decreased following exposure to MSG.252 These hormone deficiencies were reflected in the animals by small size, low reproductive ability, gross obesity, and low metabolism.

Dr Michael Schacter

Many people who are depressed are often simply deficient in nutrients or thyroid, and by giving them these nutrients, their depression frequently is alleviated, sometimes in just one or two visits. Often you don't need to go to drugs, although sometimes you will. Often depression is caused by a deficiency in the neurotransmitters for adrenaline and norepinephrine. I will frequently use the amino acid L-tyrosine, or the amino acid DL-phenylalanine. Actually, DL-phenylalanine is natural to the body in making proteins and is a precursor for D-phenylethylamine, which is frequently deficient in people who are suffering from depression. I also recommend the mineral magnesium, and vitamin B1 (thiamine) for depression. But the course of treatment really has to be individualized.

Vitamin D and other aspects of health Behaviour

The mechanism for the immunological role of vitamin D is not known, but the hormone receptor for 1,25-OHD is now recognised as one of a superfamily, the so-called 'Steroid-Thyroid-Retinoid-Superfamily'. It is understood that if these nuclear receptors and their activating substances are to recognise response elements within responsive genes, they must act in pairs and a member of the retinoid family must serve as a partner if the dimer is to function. Thus vitamin A, usually in the form of retinoic acid, is a regulator for several hormone response systems including vitamin D (Kliewer et al, 1994) (see section 3.5.2). The anti-infection properties of vitamin A are widely recognised and interactions

Disorders of the enteric nervous system

The multiple endocrine neoplasia type 2 syndromes may be associated with involvement of the gastrointestinal tract. These include multiple endocrine neoplasia (MEN) 2A, MEN 2B and isolated medullary thyroid carcinoma. These conditions are inherited as autosomal dominant traits and are as a consequence of mutation of the gene encoding the RET tyrosine kinase receptor. It is extremely important in the development of the enteric nervous system as RET null knockout mice do not develop neurons within the gut.32 There is now good evidence to show that RET is important not only for colonization of the primitive gastrointestinal tract by neural crest cells but also for their migration down the length of the gut and their further differentiation. In MEN 2A and isolated medullary thyroid carcinoma, there is an abnormality of the RET gene between codons 619 and 638, the cysteine-rich region of the gene, which results in the development of medullary thyroid carcinoma with or without...

Retinoic Acid Receptors and Gene Regulation

Vitamin A exerts its effects via retinoic acid and retinoid receptors, which are found in the nucleus of the cell. Retinol is converted to all-trans-retinoic acid and 9-cis retinoic acid in the cytoplasm. Retinoic acid influences gene activation through specific receptors which belong to the superfamily of thyroid and steroid receptors (231). Retinoic acid receptors (RARs) act as transcriptional activators for many specific target genes. The R AR is expressed as isoforms, referred to as RAR a, P, and y, and retinoid-x receptor (RXR) is also expressed as isoforms, referred to as RXR a, P, and y (232). All-trans retinoic acid is a ligand for RARs, whereas 9-cis retinoic acid is a ligand for both RARs and RXRs. 9-cis-retinoic acid is functionally distinct from all-trans-retinoic acid, and inter-conversion may exist between the two isomers. Each RAR and RXR has a specific DNA-binding domain by which these nuclear receptors may effect transcriptional activity. The DNA sequences which...


The only known function of iodine in the body is as an essential component of the thyroid hormones.2,4 The thyroid gland removes iodine from the blood and attaches it to tyrosine-containing proteins to form the thyroid hormones, thyroxine (T4) and triiodothyronine (T3). The thyroid hormones are then secreted into the bloodstream and are important regulators of cell activity and growth, both in utero and throughout life. Although they affect all tissues, they are particularly important in the development of the nervous and skeletal systems.

Hormonal Influences

The thyroid hormones thyroxine (T4) and triidothyronine (T3) regulate temperature and metabolism. In rats given intraperitoneal injections of bilberry antho-cyanins (200 mg kg day) for 5 days, significantly more T3 was found in their brains than rats given only the solvent (26 alcohol) (Saija et al., 1990). T3 enters the brain via specific transport in the capillaries, therefore anthocyanins may mediate T3 transport at the capillary level. The specific portions of the brain that contained more T3 in the bilberry-treated animals were those responsible for memory, vision, and control of sensory input the frontal, temporoparietal and occipital cortexes, and the components of the limbic system (hippocampus, thalamus, and hypothalamus).


Iodine needs increase during pregnancy for the synthesis of thyroid hormones. Maternal iodine deficiency during pregnancy can result in the enlargement of a woman's thyroid gland, development of goiter, and hypothyroidism. Maternal hypothyroidism increases the risk of a variety of poor fetal outcomes including stillbirth, spontaneous abortion, congenital anomalies, mental retardation, deafness, spastic dysplegia, and cretinism 3 . To avoid risk of harm to the fetus, maternal iodine deficiency should be corrected prior to conception. During gestation, fetal iodine deposition is approximately 75 mcg day. Results from iodine balance studies as well as iodine supplementation trials to prevent thyroid enlargement and goiter during pregnancy corroborate that an additional 70 mcg day is required to cover the pregnancy needs of 97-98 of the population during pregnancy 20 .


Thyroid hormone metabolism catalyses 5- and 5'-monodeiodination of iodothronines (including thyroid hormones). 5'-Deiodination promotes conversion of T4 to its active form T3 5-deiodination promotes conversion of T4 to the inactive reverse T3 Catalyses 5'-monodeiodination of iodothyronines (including thyroid hormones) Catalyses 5-monodeiodination of iodothyronines (including thyroid hormones)


Hyperthyroidism noun a condition in which the thyroid gland is too active and releases unusual amounts of thyroid hormones into the blood, giving rise to a rapid heartbeat, sweating and trembling. Also called thyrotoxicosis hypothyroidism noun underactivity of the thyroid gland, causing a decrease in the metabolic rate and corresponding sluggishness and weight gain


This often overlooked amino acid plays many important roles in human metabolism. L-Tyrosine is a precursor or building block to the neurotransmitters responsible for maintaining metabolic rate. L-Tyrosine is the direct precursor to stimulatory neurotransmitters such as epinephrine and noropenephrine (i.e. adrenaline) as well as certain thyroid hormones and dopamine.

Slimming patches

Basal metabolic rate is controlled to a considerable extent by the thyroid hormone tri-iodothyronine, and iodine deficiency (section results in impaired synthesis of thyroid hormone, a low metabolic rate and hence ready weight gain. Pathological overactivity of the thyroid gland results in increased synthesis and secretion of thyroid hormone, and an increased basal metabolic rate, with weight loss. The synthesis of thyroid hormone is regulated, and in the absence of thyroid disease provision of additional iodine does not increase hormone secretion except in people who were iodine deficient. Nevertheless, there are people who market various iodine-rich preparations to aid weight loss. Foremost among these are the so-called slimming patches, which contain seaweed extract as a source of iodine which is supposed to be absorbed from a small patch applied to the skin. There is no evidence that such patches have any beneficial effect at all.

Iodide I

Iodide is one of the largest atoms found in the body, yet it appears to have only one critical function. Iodide is a key component of thyroid hormone, which is made in the thyroid gland located in the neck. Thyroid hormone is constructed from iodide and the amino acid tyrosine and has two forms thyroxine (T4) and triiodothyronine (T3) based on the number of iodide atoms (3 or 4). Thyroid hormone affects most cells in the body, perhaps with the exception of the adult brain, testes, spleen, uterus, and the thyroid gland itself. Thyroid hormone promotes the activities associated with glucose breakdown and general energy metabolism and heat production. Today, thyroid hormone is prescribed mostly to treat hypothyroidism, a condition in which the thyroid gland fails to produce adequate thyroid hormone. During the growing years thyroid hormone is very important because it promotes growth and maturation of the skeleton, the central nervous system, and the reproductive organs. Iodide is best...


A goiter is a noncancerous enlargement of the thyroid gland in the front of the neck. Many conditions can cause goiter, but the most common is a lack of sufficient iodine in the diet, which is usually a result of the soil in which food is grown being iodine-poor a condition that occurs in many mountainous regions away from the sea. Iodine is required for the production of thyroid hormones, which regulate the body's metabolism.


The thyroid gland secretes mainly thyroxine (T4). This is converted to triiodothyronine (T3) in the liver and kidney by a selenium-containing enzyme type-I-iodothyronine-deiodinase.5 This conversion increases the potency of thyroid hormone and is important in enhancing its peripheral activity.


Iodine is u iiace mineral pnme function 16 regulatory Tsvo-thirds of the body's supply is found in the thyroid gland incatcd at the base o iltc ncck, just above the collarbone Here, hormones containing Iodine woik in control liie raic ol oxidation inside the ccll membrane In this way ihey regulate circulatory activity 1 hat affccts muscle tissue a- well as the metabolism of murienu. By timuluting the unction ol nervous lissue. the iodine-containing hormones also speed mental reaction and ineieasc energy enlargement of the thyroid gland. The best preventive measure is using iodized salt.

Dr Ray Wunderlich

A very high percentage of the people I see who are depressed also have imbalances like an overgrowth of candida. It is like thyroid disease. If you took all the women in my practice, from 70 to 75 percent of them would have thyroid disease, and an even higher percentage would have some form of candida, which is yeast overgrowth.

What Are Hormones

There are two ways that one region of our body can communicate with another. The first is by way of nerve impulses and the second is by way of hormones. Hormones are produced by specific organs (glands) in the body including the pituitary gland, parathyroid gland, thyroid gland, hypothalamus, pancreas, stomach, small intestine, adrenal glands, placenta, and gonads (ovaries and testicles) (Table 2.4). Hormones are released into our blood and circulate throughout our body. As they Thyroid Thyroid Increases rate of metabolism in our cells Only cells that have a specific receptor for a hormone will respond to a circulating hormone. This is an extremely accurate operation. Some hormones may have receptors on cells of only one kind of tissue in our body, while other hormones may have receptors on cells of most tissues in our body. For example, the hormone prolactin stimulates milk production in female breasts. Therefore, the cells associated with the milk-producing mammary glands will have...


However, no studies to date, in people, have looked specifically at the thermogenic effect of 7-keto-DHEA vs. DHEA. Some animal research has also shown improvements in memory and other cognitive functions. 7-keto -DHEA may also have positive effects on thyroid function. The study also found that the group getting the 7-keto-DHEA had increases in the thyroid hormone T3 without significant changes in testosterone, estradiol (estrogen), liver and kidney function tests, blood sugar vital signs, or overall caloric intake over the eight-week study.


Observed to be relatively abundant in liver, adipose tissue, and pancreatic islets, as expected, but also in heart, kidney, spleen, thymus, and stomach. Low levels were found in adrenal glands, small intestine, thyroid, and skeletal muscle. No expression was observed in testes, lung, large intestine, or brain ( 39).

Energy Boosters

Ephedra (also called Ma Huang, epitonin, and sida cordifolia) is a central nervous system stimulant that is sold as an energy booster or fat-burning supplement. Marketed as Metabolife, Xenadrine, Herbal Rush, Energy Rush, Thermoburn, or Thermofuel (among others), ephedra may delay fatigue by sparing the body's glycogen reserves during exercise. However, it can also increase blood pressure, respiration rate, heart rate, anxiety, migraines, and irregular heartbeat, and it can cause insomnia, psychosis, and nervousness. Ephedra and caffeine are often present in the same product, which can be detrimental to the heart. The maximum safe level of ephedra is 24 mg per day, but many products contain over 300 mg per dose. This supplement is contraindicated in those with a history of heart disease or hypertension, kidney or thyroid disease, seizure disorder, or diabetes.

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Building bones Maintaining bone strength Bone maintenance Blood clotting Blood synthesis Blood pressure regulation Body cell function Energy utilization DNA RNA function Regulation of body fluids Digestive function Insulin glucose function Macro-nutrient utilization Enzymes CNS function Cell energy Cell growth Thyroid function Antioxidant function Tissue repair Tooth maintenance Muscle function


While hemochromatosis is a genetically inherited disorder, not everyone with the gene has the full-blown clinical expression of the disease. About 18-20 percent escape the disease. When it is expressed, we see iron levels between fifty and one hundred times higher than normal in the liver and pancreas, 25 times higher in the thyroid and 10-15 times higher in the heart and adrenal glands.

Female Bodybuilders

Olympics, have a problem with amenorrhea or a cessation of menstruation. This seems to occur even if the women are not taking steroids. Some of the women I train reported this problem when their percentage of body fat dropped below 10-12 percent of body weight. Ideally, their percentage of body fat should be above 15 percent to prevent amenorrhea, although this level differs with each woman and will change during different times in her life. Many female athletes have said that their menstrual cycle resumes normally after slowing down on training and raising their percentage of body fat however, this is not guaranteed. Because of this, I advise female bodybuilders to cut their training schedule and increase their percentage of body fat when they have missed their menstrual cycle for over two months. However, the problem must not be ignored. Amenorrhea and irregular menstruating cycles can also be caused by other factors, such as pituitary gland tumors, premature menopause, or an...


Vitamin D works together with PTH on the bone and kidney and is necessary for intestinal absorption of calcium. Vitamin D can either be obtained from the diet or produced in the skin when it is exposed to sunlight. Insufficient vitamin D from these sources can result in rickets in children and osteomalacia in adults, conditions that result in bone deformities. Calcitonin, a hormone released by the thyroid, parathyroid, and thymus glands, lowers blood levels by promoting the deposition of calcium into bone.


Maca contains several alkaloids that are said to nourish the endocrine glands, including the pituitary, adrenals, pancreas, testes and thyroid gland. Typical of adaptogenic substances, it is believed to have a wide range of effects that include increased strength and performance, increased sexual desire, improved mental acuity, improvements in people with chronic fatigue syndrome, as well as many others effects.

What Are Plateaus

Down to accommodate imbalances in energy intake. Some of this will be hormonal (for example, thyroid hormone) while the bulk of it is due to the loss of body tissue, especially muscle. This is one of the most important reasons to do some resistance exercise during weight loss. This will help your body hold on to as much muscle as possible as you lose weight and minimize the reduction of RMR.

Chromium Cr

As mentioned, vanadium deficiency may result in reductions in growth rate, infancy survival, and hematocrit. Further, vanadium deficiency may alter the activity of the thyroid gland and its ability to utilize iodide properly. Signs of vanadium toxicity such as a green tongue, diarrhea, abdominal cramping, and alterations in mental functions have been reported in people ingesting greater than 10 milligrams of vanadium daily for extended periods of time.

What You Can Do

Cow's milk should never be given to a newborn or young child since it has a much higher level of glutamate than human milk and also is strongly associated with juvenile diabetes. Do not feed your baby soy milk. Soy milk is high in glutamate and contains estrogenic plant compounds. In addition, soy significantly inhibits the thyroid gland, which is essential for proper growth, especially brain growth. If your child has an allergy to cow's milk, use goat's milk, which is closer to human milk in composition. But do not use raw goat's milk as it may contain numerous viruses.


Barbara Ekstase

Thyroid activity is closely linked to the amount of energy you have, so it's a good idea for everyone to take an ample amount of phosphates daily. Selenium is a mineral that has received a great deal of attention in recent years. Selenium appears to have a major regulatory impact on the enzyme 5'-deiodinase, which converts T4 to T3.9 Low levels of selenium can impair thyroid conversion but excess selenium also has a negative effect on thyroid conversion. There are a lot of valuable products available to bodybuilders these days. Thyro Stak is the first supplement designed to optimize thyroid function and metabolic control, and, as such, it can be help you break through those maddening diet plateaus. 5 Tripathi, Y.B., et al. (1984). Thyroid stimulating action of Z-guggul-sterone obtained from Commiphora mukul. Planta Med. Feb(l) 78-80. 6 Tripathi, Y.B., et al. (1988). Thyroid stimulating action of Z-guggul-sterone mechanism of action. Planta Med. 54(4) 271-277. 8 Kohrie, J. (1994)....

Dr Alan Spreen

I'd love to say that correcting thyroid function is a panacea. While it doesn't work 100 percent of the time, if a patient comes in complaining of fatigue and depression that is linked with the physical findings of foods not digesting well, and cold extremities, then an underactive thyroid may be the root cause. People come and say, Oh, my husband says, 'Don't touch me with your feet at night because they're just ice cold.' These are the same people who are comfortable in a room when everybody else is boiling and they're freezing in a room when everybody else is In this kind of a situation, once I find that their blood levels of thyroid are normal, I go back to the old school of Rhoda Barnes, who, 40 or 50 years ago, did axillary temperature testing. I ask my patients to keep a record of their early morning basal body temperature. If their basal metabolic rate based on early-morning body temperatures is really low, then I consider them to be candidates for thyroid supplementation. In...

Diagnostic testing

In patients with no alarm symptoms, the Rome criteria have a positive predictive value of approximately 98 , with additional diagnostic tests providing a yield of 2 or less.105 When needed, the exclusion of an organic condition can be accomplished by utilizing inexpensive, non-invasive and easily available diagnostic tests such as complete blood cell count, erythrocyte sedimentation rate, chemistry panel, liver and thyroid function studies, urine analysis and stool examination for blood, ova and parasites. Need for other diagnostic tests should be based on history and physical examination findings. The physician should avoid the lure of having to 'rule out' an organic disease at all cost. Performing multiple tests may provide results that often are unrelated to the presenting symptom or have no clinical relevance (such as a mildly elevated sedimentation rate). Repeating tests to confirm the serendipitous findings may further increase anxiety and undermine the clinical diagnosis of...

B Plant toxins

Cassava meal is derived from the tuberous root of the cassava plant. Ingestion of this material by animals can result in enlarged thyroids, due to the presence in the meal of cyanogenic glu-cosides, the main one being linamarin. These glucosides are concentrated in the peel of the root. On hydrolysis by the enzyme linamarase, the glucosides produce hydrocyanic acid (HCN), which is highly toxic. In addition to the enzyme in the root, glucosidic intestinal enzymes and HCl can also hydrolyze the glucosides. ment for this amino acid. Thiocyanate is responsible for the goitrogenic effect of cassava, due to its effect on iodine uptake and metabolism in the thyroid, resulting in reduced output of thyroxine, which regulates tissue oxidative functions. Cyanate is known to alleviate the toxicity of an excess of dietary selenium by complexing with selenium, thus making it less available to the bird. Linseed meal, which has been known for some time to alleviate selenium toxicity in animals, has...

Trace Minerals

Iron and zinc support immune function, while chromium and zinc aid insulin action. Zinc is also essential for many other bodily functions, such as growth, development of sexual organs, and reproduction. Zinc, copper and selenium prevent oxidative damage to cells. Fluoride stabilizes bone mineral and hardens tooth enamel, thus increasing resistance to tooth decay. Iodine is essential for normal thyroid function, which is critical for many aspects of growth and development, particularly brain development. Thus, trace minerals contribute to physical growth and mental development. Role in disease prevention and treatment. In addition to clinical deficiency diseases such as anemia and goiter, research indicates that trace minerals play a role in the development, prevention, and treatment of chronic diseases. A marginal status of several trace minerals has been found to be associated with infectious diseases, disorders of the stomach, intestine, bone, heart, and liver, and cancer, although...

Dr Hyla Cass

The thyroid is a very important component of the immune system. When the thyroid isn't working properly, the immune system is impaired, and this sets up a vicious cycle. You have a person who is depleted and anxious they're told by regular doctors it's all in their head, that there's nothing physically wrong with them. So then they feel worse. A large number of patients who come to see me have thyroiditis. I really can't emphasize it enough because this can lead to the mixed infection syndrome that we see so much of parasites, candida, and even the viral syndromes--the Epstein Barr virus and the cytomegalovirus. To treat thyroiditis, I've done nutritional consults on people that were under the care of other physicians. When I suggested that they had thyroiditis and that it was to be treated with low doses of thyroid hormones, I was met with skepticism from the other doctors. When people have these longstanding chronic conditions, they can become extremely depressed. They feel like...


Numerous mechanisms have been proposed to explain the effects of soy, such as an altered hepatic metabolism of cholesterol that includes an altered LDL receptor activity, altered thyroid hormone and altered estrogenic activity.91 The phytosterols and the saponins in soy can block the absorption of cholesterol and bile acids or increase their excretion from the body, thus lowering blood cholesterol levels.77,92 Recent research shows that the isoflavones in soy may also be involved. They are known to prevent the oxidation of LDL cholesterol, inhibit proliferation in the artery wall, lower blood cholesterol levels, and attenuate events leading to the formation of blood clots. Genistein is a well-known inhibitor of tyrosine kinase, an enzyme active in the cascade of events that occurs in the formation of clots, as well as in tissues actively producing plaque.91,93 The isoflavones also alter the activity of cytokines and specific growth factors that influence lesion formation, have an...

Canola meal

Canola still has enough goitrogen activity to result in measurable increases in thyroid weight, although this does not appear to be a problem affecting the performance of poultry. The tannin levels in canola can also be relatively high, with up to 3 for some cultivars. Again, research has shown that the canola tannins have little influence in the utilization of the protein in diets containing appreciable levels of the meal.

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