Glutamine was first isolated in 1883 from beet juice. Glutamine is one of the most abundant free amino acids in the human body (muscle and plasma), comprising approximately 50% of the free amino acid pool in the blood and skeletal muscle.12 Glutamine is considered a nonessential amino acid (dispensable) since it can be produced in the body from other amino acids, namely, glutamic acid, in the liver and skeletal muscle. The skeletal muscle is the most active tissue for glutamine synthesis, storage, and release, thus playing a critical role in the maintenance of plasma glutamine concentrations. However, under certain physiological conditions

FIGURE 14.1 Chemical structure of glutamine.

(trauma, infection, stress), glutamine can become a conditionally essential amino acid (indispensable), and exogenous sources (diet and supplements) may be required to meet the needs of the body.

Your Heart and Nutrition

Your Heart and Nutrition

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