Like most minerals, magnesium plays a major role as a cofactor for numerous metal-loenzymes in the body, many of which are important for DNA, RNA, and protein synthesis; cellular growth; reproduction; and ATP production [96]. Magnesium is, therefore, critical for maternal and fetal growth and development during pregnancy. It is also involved in regulation of cardiovascular function, apparently playing a major role in modulating blood pressure in some populations [97-99]. Some studies also suggest that magnesium can help regulate blood glucose concentration in people with diabetes [100]. The best dietary sources of this mineral include leafy vegetables, whole grains, and nuts.

Because of magnesium's possible role in helping regulate blood pressure, there has been interest in determining whether magnesium supplementation during pregnancy might decrease the risk of pre-eclampsia and its complications [101]. Although there is relatively good evidence from clinical trials that magnesium administered intravenously can dramatically decrease preeclampsia, the data from oral supplementation trials are not convincing [102, 103]. It should be noted, however, that most studies conducted to date have not employed adequate study design and proper control groups to test the effects of oral magnesium administration on pregnancy outcome variables. Thus, further research is warranted. Recommendations

Magnesium supplementation is not generally indicated during pregnancy. It is noteworthy that excessive magnesium intake from nonfood sources can cause gastrointestinal distress, and the IOM's UL for this mineral (350 mg/day) refers to intake only from supplements and medications such as milk of magnesia, not from food sources.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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