Preeclampsia is a multi-organ disease that occurs after 20 weeks gestation and is characterized by the development of proteinuria and hypertension. It is specific to pregnancy and complicates 5-7% of pregnancies [1]. It falls into the larger category of hypertensive disorders of pregnancy, which is addressed briefly within this chapter. The exact etiology or pathophysiology of this disorder is poorly understood. Additionally, there are no well-established methods of primary prevention or of reliable and cost-effective screening. Yet, preeclampsia is associated with increased maternal mortality and morbidity including placental abruption, acute renal failure, cerebrovascular and cardiovascular complications, and disseminated intravascular coagulation [2].

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