Protease and amylase inhibitors are found in legumes and certain oilseeds (Whitaker, 1997). Protease inhibitors are easily denatured by heat, as are the amy-lase inhibitors. The antinutrient activity of protease inhibitors is due to their growth inhibitory effect and pancreatic hypertrophy. While potential health benefits of protease inhibitors remain unclear, lower incidences of pancreatic cancer have been observed in populations where the intake of soybean and its products is high.
Amylase inhibitors are known to have hypoglycemic effects, and trypsin inhibitors in soybean are known to have anticarcinogenic properties and are also effective in lowering caloric intake.
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