Where Does Low Density Lipoprotein Come from and What Does It Do

You will also recall that the liver packages up cholesterol and fat (triglyceride) into very low density lipoproteins (VLDLs), which are then released into the blood. As VLDLs circulate, they unload their fat cargo with most of it going to fat (adipose) tissue and other tissue such as skeletal muscle and the heart. As they lose their fat, VLDLs become LDLs, which are mostly cholesterol. As LDLs circulate they drop off cholesterol in tissue throughout the body and are eventually removed from the blood by the liver and other tissue.

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