Glucagon works in a manner that is generally opposite to insulin. It will labor to increase blood glucose concentration, thereby returning it toward normal levels. To accomplish this, glucagon promotes the breakdown of liver glycogen to glucose, which is released into circulation.
Glucagon will also promote another activity in our liver that will generate glucose. The process is called gluconeogenesis, which literally means to create new glucose if you read its root words right to left. In this process, certain amino acids, lactate (lactic acid), and glycerol from our circulation will be taken up by our liver and used to make glucose. Like the glucose generated from glycogen breakdown, this glucose can also be released into our blood to maintain blood glucose levels.
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