Preface

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The immediate predecessor of Modern Nutrition in Health and Disease was Dietotherapy, published in 1945 and edited by Drs. Michael Wohl and Robert Goodhart. With the same editors, its successor, the first edition of Modern Nutrition in Health and Disease, appeared in 1955. Its original objective has remained in succeeding editions: to serve as a comprehensive authoritative text and reference source reviewing the history, scientific base, and practice of nutrition for students, practitioners, and educators. The broad scope of nutritional sciences has relevance to all basic and applied biologic sciences, medicine, dentistry, dietetics, nursing, pharmacy, public health, and public policy.

This edition has 115 chapters and multiple sections of an Appendix, updated by 169 authors in 10 countries and from many scientific disciplines. To these authors we express our deep appreciation.

Thirty-five chapters review specific dietary components in depth; 18 others are concerned with the role of nutrition in integrated biologic systems; 5 review aspects of nutrition assessment; 41 cover a variety of clinical disorders; and 13 discuss public health and policy issues.

Thirty-six new chapters have been introduced designed to provide better understanding of the role of nutrition in integrated biologic systems and in other areas. These include general and specific aspects of molecular biology and genetics, ion channels, transmembrane signaling, and other topics-all in tutorial form. The matter of essential and conditionally essential nutrients is reviewed historically in the opening chapter and considered in separate chapters on individual essential nutrients and in those on taurine, homocysteine, glutamine, arginine, choline, and carnitine.

There are added chapters on nutritional issues in pediatrics, cardiovascular disorders, gastroenterology, cancer, hematology, and rheumatology. In the field of public health, new chapters address vegetarian diets, anthropology, "alternative" nutritional therapies, nutritional priorities in less industrialized countries, and risk assessment of nutrition-related environmental chemicals.

An extensive Appendix includes dietary reference recommendations from various national (including the new 1997 and 1998 U.S. Dietary Reference Intakes) and international agencies, multiple anthropometric tables, nutrient and nonnutrient contents of foods and beverages, numerous therapeutic diets and exchange lists, and other sources of nutritional information.

Relevant quantitative data have been expressed both in conventional and in international system (SI) units. The widespread use of the SI units in major publications in the United States and especially in other countries makes dual unitage useful to our readers.

We have endeavored to provide the breadth of coverage and quality of content required by this ever-changing discipline in its basic and clinical dimensions. We invite the comments and suggestions of our readers.

MAURICE EDWARD SHILS

Winston-Salem, NC

JAMES ALLEN OLSON

Ames, A

MOSHE SHIKE

New York City, NY

A. CATHARINE ROSS

University Park, PA

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