Types of evidence linking diet and diseases of affluence

The main evidence linking diet with the diseases of affluence is epidemiological; animal studies are used to test hypotheses derived from epidemiology, and to test the effects of specific nutritional changes. When there is a substantial body of evidence then there can be direct intervention studies, in which the diets of large numbers of people are changed (e.g. by providing supplements of nutrients for which there is epidemiological evidence of a protective effect), and they are followed for 5—10 or more years, to see whether the intervention has any effect on disease incidence or mortality.

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