Tissue reserves of metabolic fuels

In the fed state, as well as providing for immediate energy needs, substrates are converted into storage compounds for use in the fasting state. There are two main stores of metabolic fuels:

  • triacylglycerols in adipose tissue;
  • glycogen as a carbohydrate reserve in liver and muscle.

In addition, there is an increase in the synthesis of tissue proteins after a meal, as a result of the increased availability of metabolic fuel to provide ATP for protein synthesis (section

In the fasting state, which is the normal state between meals, these reserves are mobilized and used. Glycogen is a source of glucose, while adipose tissue provides both fatty acids and glycerol from triacylglycerol. Some of the relatively labile protein laid down in response to meals is also mobilized in fasting, and the amino acids are used both as a metabolic fuel and, more importantly, a source of citric acid cycle intermediates for gluconeogenesis.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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