Nucleotides consist of a purine or pyrimidine base linked to the five-carbon sugar ribose. The base plus sugar is a nucleoside; in a nucleotide the sugar is phosphorylated. Nucleotides may be mono-, di- or triphosphates.
Figure 3.1 shows the nucleotides formed from the purine adenine — the adenine nucleotides, adenosine monophosphate (AMP), adenosine diphosphate (ADP) and adenosine triphosphate (ATP) — as well as the nucleotide triphosphates formed from the purine guanine and the pyrimidine uracil (see also section 10.3.2 for a discussion of the role of cyclic AMP in metabolic regulation and hormone action).
In the nucleic acids (DNA and RNA; sections 9.2.1 and 9.2.2 respectively) it is the purine or pyrimidine that is important, carrying the genetic information. However, in the link between energy-yielding metabolism and the performance of physical and chemical work, what is important is the phosphorylation of the ribose. Although most reactions are linked to adenosine triphosphate, a small number are linked to guanosine triphosphate (GTP; see, for example, sections 5.7 and 188.8.131.52) or uridine triphosphate (UTP; section 5.5.3).
Was this article helpful?
Statistics For Obesity Are Rising And The Majority Of People Are Not Getting Enough Exercise Nor Are Having Any Regard For Their Health! Will You Finally Make Good On Your Promise And Set Your Goals To Improve Your Fitness And Live The Healthy Lifestyle You Want? With A Little Bit of Motivation, You Can Set Yourself On the Correct Path To Losing Weight And Feeling Great Using Nothing But Purely Natural Means!