Alcantara, O., Javors, M. and Boldt, D.H. (1991) Induction of protein kinase C mRNA in cultured lymphoblastoid T-cell by iron-transferrin but not soluble iron. Blood 77, 1290-1297.

Alcantara, O., Obeid, L., Hannun, Y., Ponka, P and Boldt, D.H. (1994) Regulation of protein kinase C (PKC) by iron: effect of different iron compounds on PKC-beta and PKC-alpha expression and role of the 5' flanking region of the PKC-beta gene in the response to ferric transferrin. Blood 84, 3510-3517.

Bagchi, K., Mohanram, M. and Reddy, V. (1980) Humoral immune response in children with iron deficiency. British Medical Journal 280, 1249-1251.

Barry, D.M.J. and Reeve, A.W. (1977) Increased incidence of gram negative neonatal sepsis with intramuscular iron administration. Pediatrics 60, 908-912.

Bhaskaram, C. and Reddy, V. (1975) Cell-mediated immunity in iron and vitamin-deficient children. British Medical Journal 3, 522.

Bhaskaram, P, Sherada, K., Sivakumar, B., Rao, K.V and Nair, M. (1989) Effect of iron and vitamin A deficiencies on macrophage function in children. Nutrition Research 9, 35-45.

Boelaert, J.R., Cantinieaux, B.F, Hariga, C.F and Fondu, FIG. (1990) Recombinant ery-thropoietin reverses polymorphonuclear granulocyte dysfunction in iron-overloaded dialysis patients. Nephrology Dialysis Transplantation 5, 504-507.

Brieland, J.K. and Fantone, J.C. (1991) Ferrous iron release from transferrin by human neutrophil-derived superoxide anion: effect of pH and iron saturation. Archives of Biochemistry and Biophysics 284, 78-83.

Brock, J.H. (1992) Iron and the immune system. In: Lauffer, R.B. (ed.) Iron and Human Disease. CRC Press, Boca Raton, Florida, pp. 161-178.

Brock, J.H. (1993) Iron and immunity. Journal of Nutritional Immunology 2, 47-106.

Bryan, C.F, Leech, S.H., Kumar, P, Gaumer, R., Bozelka, B. and Morgan, J. (1991) The immune system in hereditary hemochromatosis: a quantitative and functional assessment of cellular arm. American Journal of Medical Science 301, 55-61.

Byrd, T.F (1997) Tumor necrosis factor alpha promotes growth of virulent mycobac-terium tuberculosis in human monocytes: iron-mediated growth suppression is correlated with decreased release of TNF-alpha from iron-treated infected monocytes. Journal of Clinical Investigation 99, 2518-2529.

Cantinieaux, B.F, Hariga, C., Ferster, A., De-Maertaere, E., Toppet, M. and Fondu, P (1987) Neutrophil dysfunctions in thalassemia major: the role of cell iron overload. European Journal of Haematology 39, 28-34.

Cantinieaux, B., Janssens, A., Boelaert J.R., Lejeune, M., Vermylen, C., Kerrels, V., Cornu, J., Winand, J. and Fondu, P (1999) Ferritin-associated iron induces neutrophil dysfunction in hemosiderosis. Journal of Laboratory and Clinical Medicine 133, 353-361.

Cazzalo, M., Bergamaschi, G., Dezza, L. and Arosio, P (1990) Manipulation of cellular iron metabolism for modulating normal and malignant cell proliferation: achievement and prospects. Blood 75, 1903-1919.

Chandra, R.K. and Saraya, A.K. (1975) Impaired immunocompetence associated with iron deficiency. Journal of Pediatrics 86, 899-902.

Chapman, D.E., Good, M.F, Powell, L.W. and Halliday, J.W. (1988) The effects of iron, iron-binding proteins and iron overload on human natural killer cell activity. Journal of Gastroenterology and Hepatology 3, 9-17.

Chwang, L.C., Soemantri, A.G. and Pollitt, E. (1988) Iron supplementation and physical growth of rural Indonesia children. American Journal of Clinical Nutrition 47, 496-501.

Cook, J.D. and Skikne, B.S. (1989) Iron deficiency and diagnosis. Journal of Internal Medicine 226, 349-355.

Dallman, PR. (1987) Iron deficiency and the immune response. American Journal of Clinical Nutrition 46, 329-334.

Dhur, A., Galan, P, Hannoun, C., Hout, K. and Hercberg, S. (1990) Effects of iron deficiency upon the antibody response to influenza virus in rats. Journal of Nutritional Biochemistry 1, 629-634.

Dwyer, J., Wood, C., McNamara, J., Williams, A., Andiman, W., Rink, L., O'Connor, T. and Pearson, H. (1987) Abnormalities in the immune system of children with beta-thalassaemia major. Experimental Immunology 68, 621-629.

Escalona, E., Malave, I., Rodriguez, E., Araujo, Z., Inati, J., Arends, A. and Perdomo, Y. (1987) Mitogen-induced lymphoproliferative responses and lymphocyte sub-

populations in patients with sickle disease. Journal of Clinical and Laboratory Immunology 22, 191-196.

Fairbank, V.F (1988) Iron-deficiency anemia. In: Mazza, J.J. (ed.) Manual of Clinical Hematology. Little Brown, Boston, Massachusetts, pp. 1-48.

Flament, J., Goldman, M., Waterlot, Y., Dupont, E., Wybran, J. and Vanherweghem, J.L. (1986) Impairment of phagocyte oxidative metabolism in hemodialyzed patients with iron overload. Clinical Nephrology 25, 227-230.

Galan, P, Thibault, H., Preziosi, P and Hercberg, S. (1992) Interleukin-2 production in iron-deficient children. Biological Trace Element Research 32, 421-426.

Glassman, A.B., Deas, D.V., Berlinsky, FS. and Bennett, C.E. (1980) Lymphocytic blast transformation and peripheral lymphocyte percentages in patients with sickle cell disease. Annals of Clinical and Laboratory Science 10, 9-12.

Guglielmo, P, Cunsolo, F, Lombardo, T., Sortino, G., Giustolisi, R., Cacciola, E. and Cacciola, E. (1984) T-cell subset abnormalities in thalassemia intermedia: possible evidence for thymus functional deficiency. Acta Haematologia 72, 361-367.

Helyar, L. and Sherman, A.D. (1987) Iron deficiency and interleukin-1 production by rat leucocytes. American Journal of Clinical Nutrition 46, 346-352.

Helyar, L. and Sherman, R.A. (1992) Moderate and severe iron deficiency lowers numbers of spleen T lymphocyte and B lymphocyte subsets in the C57BL/6 mouse. Nutrition Research 12, 1113-1122.

Heresi, G., Pizarro, F, Olivares, M., Cayazzo, M., Hertampg, E., Walter, T., Murphy, R.J. and Stekel, A. (1995) Effect of supplementation with iron-fortified milk on incidence of diarrhea and respiratory infection in urban-resident infants. Scandinavian Journal of Infectious Disease 27, 385-389.

Hernandez, P, Cruz, C., Santos, M.N. and Ballester, J.M. (1980) Immunologic dysfunction in sickle cell anemia. Acta Haematologica 63, 156-161.

Humbert, J.R. and Moore, L.J. (1983) Iron deficiency and infection: a dilemma. Journal of Pediatric Gastroenterology and Nutrition 2, 403-406.

Hussein, M.A., Hassan, H., Abdel-Ghaffer, A.A. and Salen, S. (1988) Effects of iron supplementation on the occurrence of diarrhea among children in rural Egypt. Food and Nutrition Bulletin 10, 35-39.

Jiang, X. and Baldwin, C.L. (1993) Iron augments macrophage-mediated killing of Brucella abortus alone and in conjunction with interferon-gamma. Cellular Immunology 148, 397-407.

Joynson, D.H.M., Murray-Walker, D., Jacobs, A. and Dolby, A.E. (1972) Defects of cellmediated immunity in patients with iron-deficiency anaemia. Lancet ii, 1058-1059.

Kaplan, J., Sanarik, S., Gitlin, J. and Lusher, J. (1984) Diminished helper to suppressor lymphocyte ratios and natural killer cell activity in recipients of repeated blood transfusions. Blood 64, 308-310.

Kemahli, A.S., Babacan, E. and Cavdar, A.O. (1988) Cell mediated immune responses in children with iron deficiency and combined iron and zinc deficiency. Nutrition 8, 129-136.

Kemp, J.D. (1993) The role of iron and iron binding proteins in lymphocyte physiology and pathology. Journal of Clinical Immunology 13, 81-92.

Keush, G.T. (1990) Micronutrients and susceptibility to infection. Annals of the New York Academy of Science 589, 181-189.

Kochanowski, B.A. and Sherman, A.R. (1985) Decreased antibody formation in iron-deficient rat pups - effect of iron repletion. American Journal of Clinical Nutrition 41, 278-284.

Krantman, H.J., Young, S.R., Ank, B.J., O'Donnell, C.M., Rachelefsky, G.S. and Stiehm, E.R. (1982) Immune function in pure iron deficiency. American Journal of Diseases of Children 136, 840-844.

Kuvibidila, S. and Wade, S. (1987) Macrophage function as studied by the clearance of 125I-labeled polyvinylpyrrolidone in iron-deficient and iron-replete mice. Journal of Nutrition 117, 170-176.

Kuvibidila, S.R., Baliga, B.S. and Suskind, R.M. (1981) Effects of iron deficiency anemia on delayed cutaneous hypersensitivity in mice. American Journal of Clinical Nutrition 34, 2635-2640.

Kuvibidila, S.R., Baliga, B.S. and Suskind, R.M. (1982) Generation of plaque forming cells in iron-deficient anemic mice. Nutrition Reports International 26, 861-871.

Kuvibidila, S., Nauss, K.M., Baliga, B.S. and Suskind, R.M. (1983a) Impairment of blas-togenic response of splenic lymphocytes from iron-deficient mice: in vivo repletion. American Journal of Clinical Nutrition 37, 15-25.

Kuvibidila, S.R., Baliga, B.S. and Suskind, R.M. (1983b) The effects of iron deficiency on cytolytic activity of mice spleen and peritoneal cells against allogenic tumor cells. American Journal of Clinical Nutrition 38, 238-244.

Kuvibidila, S., Baliga, S.B. and Suskind, R.M. (1989) Consequences of iron deficiency on infection and immunity. In: Lebenthal, E. (ed.) Textbook of Gastroenterology and Nutrition in Infancy, 2nd edn. Raven Press, New York, pp. 423-431.

Kuvibidila, S., Dardenne, M., Savino, W. and Lepault, F (1990) Influence of iron-deficiency anemia on selected thymus functions in mice: thymulin biological activity, T-cell subsets and thymocyte proliferation. American Journal of Clinical Nutrition 51, 228-232.

Kuvibidila, S., Baliga, B.S. and Murthy, K.K. (1991) Impaired protein kinase C activation as one of the possible mechanisms of reduced lymphocyte proliferation in iron deficiency in mice. American Journal of Clinical Nutrition 54, 944-950.

Kuvibidila, S., Baliga, B.S. and Murthy, K.K. (1992) Alteration of interleukin-2 (IL-2) production in iron deficiency anemia. Journal of Nutritional Immunology 1, 81-88.

Kuvibidila, S., Yu, L., Ode, D. and Warrier, R.P (1993) The immune response in protein-energy malnutrition and single nutrient deficiencies. In: Klurfeld, D.M. (ed.) Nutrition and Immunology. Plenum Press, New York, pp. 121-155.

Kuvibidila, S.R., Baliga, B.S., Warrier, R.P and Suskind, R.M. (1998) Iron deficiency reduces the hydrolysis of cell membrane phosphatidyl inositol-4,5-bisphosphate during splenic lymphocyte activation in C57BL/6 mice. Journal of Nutrition 128, 1077-1083.

Kuvibidila, S., Kitchens, D. and Baliga, B.S. (1999) In vivo and in vitro iron deficiency reduces protein kinase C activation and translocation in murine splenic and purified T-cells. Journal of Cellular Biochemistry 74, 468-478.

Kuvibidila, S.R., Porretta, C., Baliga, B.S. and Leiva, L.E. (2001) Reduced thymocyte proliferation but not increased apoptosis as a possible cause of thymus atrophy in iron-deficient mice. British Journal of Nutrition 86, 157-162.

Latunde-Dada, G.O. and Young, A.P (1992) Iron deficiency and immune responses. Scandinavian Journal of Immunology 11 (Suppl.), 207-209.

Lucas, J.J., Szepesi, A., Domenico, J., Takase, K., Tordai, A., Terada, N. and Gelfand, E.W. (1995) Effects of iron-depletion on cell-cycle progression in normal human T lymphocytes: selective inhibition of appearance of the cyclin A-associated component of the p33cdk2 kinase. Blood 86, 2268-2280.

MacDougall, L.G., Anderson, R., McNab, G.M. and Katz, J. (1975) Immune response in iron-deficient children: impaired cellular defence mechanisms with altered humoral components. Journal of Pediatrics 86, 833-843.

McFarlane, H., Reddy, S., Adcock, K.J., Adeshina, H., Cooke, A.R. and Akene, J. (1970) Immunity, transferrin, and survival in kwashiorkor. British Medical Journal 4, 268-270.

Mencacci, A., Cenci, E., Boelaert, J.R., Bucci, P, Mosci, P, Fe d'Ostiani, C., Bistoni, F and Romani, L. (1997) Iron overload alters innate and T helper cell response to Candida albicans in mice. Journal of Infectious Disease 175, 1467-1476.

Menendez, C., Kahigwa, E., Hirt, R., Vounatsou, P, Aponte, J.J., Font, F, Acosta, C.J., Schellenberg, D.M., Galindo, C.M., Kimario, J., Urassa, H., Brabin, B., Smith, T.A., Kitua, A.Y., Tanner, M. and Alanso, P.L. (1997) Randomised placebo-controlled trial of iron supplementation and malaria chemoprophylaxis for prevention of severe anaemia and malaria in Tanzanian infants. Lancet 350, 844-850.

Munn, C.G., Markenson, A.L., Kapadia, A. and De Sousa, M. (1981) Impaired T-cell mitogen responses in some patients with thalassemia intermedia. Thymus 3, 119-128.

Murakawa, H., Bland, C.E., Willis, W.T. and Dallman, P.R. (1987) Iron deficiency and neutrophil function: different rates of correction of the depressions in oxidative burst and myeloperoxidase activity after iron treatment. Blood 69, 1464-1468.

Murray, M.J., Murray, A.B., Murray, N.J. and Murray, M.B. (1978a) Diet and cerebral malaria: the effect of famine and re-feeding. American Journal of Clinical Nutrition 31, 57-61.

Murray, M.J., Murray, A.B., Murray, M.B. and Murray, C.J. (1978b) The adverse effect of iron repletion on the course of certain infections. British Medical Journal 2, 1113-1115.

Nalder, B.N., Mahoney, A.W., Ramakrishnan, R. and Hendricks, D.G. (1972) Sensitivity of the immunological response to nutritional status of rats. Journal of Nutrition 102, 535-542.

Neckers, L.M. and Cossman, J. (1983) Transferrin receptor induction in mitogen-stimu-lated human T lymphocytes is required for DNA synthesis and cell division and is regulated by interleukin-2. Proceedings of the National Academy of Sciences of the USA 80, 3494-3498.

Neckers, L.M., Yenokida, G. and James, S.P (1984) The role of transferrin receptor in human B lymphocyte activation. Journal of Immunology 133, 2437-2441.

O'Brien-Ladner, A.R., Blumer, B.M. and Wesselius, L.J. (1998) Differential regulation of alveolar macrophage-derived interleukin-1 beta and tumor necrosis factor-alpha by iron. Journal of Laboratory and Clinical Medicine 132, 497-506.

Omara, FO. and Blakley, B.R. (1994) The effects of iron deficiency and iron overload on cell-mediated immunity in the mouse. British Journal of Nutrition 72, 899-909.

Oppenheimer, S.J., Gibson, FD., MacFarlane, S.B., Moody, J.B., Harrison, C., Spencer, A. and Bunari, O. (1986) Iron supplementation increases prevalence and effects of malaria: report on clinical studies in Papua New Guinea. Transactions of the Royal Society of Tropical Medicine and Hygiene 80, 603-612.

Parmley, R.T., Hajdu, I. and Denys, FR. (1983) Ultrastructural localization of the trans-ferrin receptor and transferrin on marrow cell surfaces. British Journal of Haematology 54, 633-641.

Patruta, S.L. and Horl, W. (1999) Iron and infection. Kidney International 55(Suppl. 69), S125-S130.

Payne, S.M. and Finkelstein, R.A. (1978) The critical role of iron in host-bacterial interaction. Journal of Clinical Investigation 61, 1428-1440.

Perkkio, M.V, Jansson, L.T., Dallman, PR., Siimes, M.A. and Savilahti, E. (1987) sIgA and IgM-containing cells in intestinal mucosa of iron deficient rats. American Journal of Clinical Nutrition 46, 341-345.

Prema, K., Ramalakshmi, B.A., Madhavapeddi, R. and Babu, S. (1982) Immune status of anaemic pregnant women. British Journal of Obstetrics and Gynaecology 89, 222-225.

Sainte-Marie, J., LaFont, E.I., Pecheur E.I., Favero, J., Philippot, J.R. and Bienvenue, A. (1997) Transferrin receptor functions as a signal-transduction molecule for its own recycling via increases in the internal Ca2+ concentration. European Journal of Biochemistry 250, 689-697.

Santos, PC. and Falcao, R.P (1990) Decreased lymphocyte subsets and K-cell activity in iron deficiency anemia. Acta Haematologica 84, 118-121.

Smith, A.W., Hendrickse, R.G., Harrison, C., Hayes, R.J. and Greenwood, B.M. (1989) The effects on malaria of treatment of iron-deficiency anaemia with oral iron in Gambian children. Annals of Tropical Paediatrics 9, 17-23.

Snow, R.W., Byass, P, Shenton, FC. and Greewood, B.M. (1991) The relationship between anthropometric measurements and measurements of iron status and susceptibility to malaria in Gambian children. Transactions of the Royal Society of Tropical Medicine and Hygiene 85, 584-589.

Spear, A.T. and Sherman, A.R. (1992) Iron deficiency alters DMBA-induced tumor burden and natural killer cell cytotoxicity in rats. Journal of Nutrition 122, 46-55.

Strauss, R.G. (1978) Iron deficiency, infections, and immune function: a reassessment. American Journal of Clinical Nutrition 31, 660-666.

Srikantia, S.G., Prasad, J.S., Bhaskaram, C. and Krishnamachari, K.A. (1976) Anaemia and the immune response. Lancet i, 1307-1309.

Swarup-Mitra, S. and Sinha, A.K. (1984) Cell-mediated immunity in nutritional anaemia. Indian Journal of Medical Research 79, 354-362.

Testa, U., Khun, L., Petrini, M., Quaranta, M.T., Pelosi, E. and Peschle, C. (1991) Differential regulation of iron regulatory element-binding protein(s) in cell extracts of activated lymphocytes versus monocytes-macrophages. Journal of Biological Chemistry 266, 13925-13930.

Thibault, H., Galan, P, Selz, F, Preziosi, P, Olivier, C., Badoual, J. and Hercberg, S. (1993) The immune response in iron-deficient young children: effect of iron supplementation on cell-mediated immunity. European Journal of Pediatrics 152, 120-124.

Tormey, D.C., Imrie, R.C. and Mueller, G.C. (1972) Identification of transferrin as a lymphocyte growth promoter in human serum. Experimental Cell Research 74, 163-169.

Vydyborets, S.V. (2000) An analysis of the immunity indices of patients with iron deficiency anemia. Likarska Sprava 3-4, 71-75.

Walter, T., Arredondo, S., Arevalo, M. and Stekel, A. (1986) Effect of iron therapy on phagocytosis and bactericidal activity in neutrophils of iron-deficient infants. American Journal of Clinical Nutrition 44, 877-882.

Walter, T., Olivares, M., Pizzaro, F and Munoz, C. (1997) Iron, anemia, and infection. Nutrition Reviews 55, 111-124.

Waterlot, Y., Cantinieaux, B., Hariga-Muller, C., De-Maertelaere-Laurent, E., Vanherweghem, J.L. and Fondu, P (1985) Impaired phagocytic activity of neu-trophils in patients receiving hemodialysis: the critical role of iron overload. British Medical Journal 291, 501-504.

Wu, W.H., Meydani, M., Meyani, S.N., Burklund, PM., Blumberg, J.B. and Munro, H.N. (1990) Effects of dietary iron overload on lipid peroxidation, prostaglandin synthesis and lymphocyte proliferation in young and old rats. Journal of Nutrition 120, 280-289.

Yetgin, S., Altay, C., Ciliv, G. and Laleli, Y. (1979) Myeloperoxidase activity and bactericidal function of PMN in iron deficiency. Acta Haematologica 61, 10-14.

Yip, R. and Dallman, PR. (1996) Iron. In: Ziegler, E. and Filer, L.J., Jr (eds) Present Knowledge in Nutrition, 7th edn. International Life Sciences Institute Press, Washington, DC, pp. 276-292.

How To Bolster Your Immune System

How To Bolster Your Immune System

All Natural Immune Boosters Proven To Fight Infection, Disease And More. Discover A Natural, Safe Effective Way To Boost Your Immune System Using Ingredients From Your Kitchen Cupboard. The only common sense, no holds barred guide to hit the market today no gimmicks, no pills, just old fashioned common sense remedies to cure colds, influenza, viral infections and more.

Get My Free Audio Book

Post a comment