Some patients with Hirschsprung's disease continue to have problems postoperatively; this may be because of residual disease or association with neuronal dysplasia. Investigations include barium studies to delineate strictures or leaks, and further biopsy to exclude residual aganglionic bowel. If the definitive operation fails because of an impassable stricture, disruption or residual disease, further secondary surgery may be necessary and a different operation may then lead to an acceptable result.

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