Guggulsterones Turn Up the Heat to Burn More

by Derek Cornelius

Commiphora mukul is an herb known as guggul. Just as that plant has unique and interesting names, so it also has unique and interesting effects on the human body.

Guggul is a tree that grows in India that exudes a resinous sap from its bark. The resin has been used for centuries in India's traditional Ayurveda medicine. In our modern world of advanced chemistry the sap is processed and purified and then standardized for its active constituents—Z and E guggulsterones. The two compounds are plant sterols that have a high degree of human bioactivity and have been shown in studies to affect many biological processes, including thyroid metabolism, cholesterol management and dermal, or skin, function. In each of those areas guggulsterones were shown to be highly effective modulators with near-druglike potency.

Bodybuilders are concerned with not only building solid muscle tissue but also reducing the amount of fat deposits. You may weigh 240 pounds and have a tremendous amount of muscular development, but if you have two inches of subcutaneous fat all over your body, you won't look all that great. You definitely won't be aesthetically pleasing, and some people might even call you doughboy. A thyroid-stimulating substance might be exactly what you need.

I first became interested in guggulsterones when I noticed studies on their thyroid-stimulating properties. I discovered that guggulsterones have a direct stimulating action on the thyroid gland through enzymatic mechanisms. One study concluded that they're a viable option for the treatment of hy-pothyroidal conditions. The warm feeling, the sweating and the rise in body temperature confirm guggulsterone's thyroid-stimulating ability. That's good news for those of us who are trying to lose weight—especially adipose tissue, or fat stores. When the thyroid gland is stimulated, it produces more thyroid hormones, such as thyroxin, which have a profound effect on the rate of metabolism, including a direct catabolic effect on adipose tissue. That means guggulsterones will stimulate your thyroid to produce more thyroid hormones, which in turn will raise your metabolic rate and burn more fat.

Guggulsterones by themselves have been shown to work very well for fat loss, but I've found a combination that's nothing short of amazing— guggulsterones and an EC A stack such as Adipokinetix. We already know that Adipokinetix is an extremely potent fat burner, but it does its work outside the realm of the thyroid. It made sense to me that if one could combine the fat-burning effects of the thyroid hormones with those of the adrenergic hormones (e.g., adrenaline), something very dramatic would result. Also, ECA stacks tend to decrease the amount of thyroid hormones circulating in the blood over time. Guggulsterones do a great job of inhibiting that reduction, thus keeping all physiological fat-burning systems operating at a maximum level.

The final ways in which guggulsterones can benefit in the fight to burn fat involve ketogenic diets and growth hormone use. Over time ketogenic diets tend to reduce the thyroid's effectiveness by reducing the conversion of T4 to the more potent T3. Guggulsterones won't do anything to increase the conversion, but they will cause more T4 release, which in turn should increase T3 to some extent. Furthermore, although T4 is not as potent a metabolic regulator, it is functional and should inherently help boost the metabolic rate. Regarding GH use, anyone who has taken this potent hormone knows that it vastly reduces the amount of thyroid hormones that are produced by the thyroid gland. Again, although I've never tried it and don't know of anyone who has, guggulsterones should help lessen the thyroid-hormone-reducing effect.

Although their fat-burning properties are what we're most interested in, guggulsterones also have an extremely beneficial effect on cholesterol and

ìuggulsterones have a direct stimulating action on the thyroid gland through enzymatic mechanisms. One study concluded that hiey're a viable option for the treatment of hypothyroidal conditions.

triglyceride levels. Numerous clinical studies have shown that they cause a 14 to 27 percent decrease in total cholesterol in a four-to-12-week period, while triglyceride levels drop 22 to 30 percent. Even more interesting is the fact that guggulsterones support a high high-density lipoprotein (HDL), or "good" cholesterol, level and a low low-density lipoprotein (LDL), or "bad" cholesterol, level. Study after study confirms that guggulsterones are as potent as many of the current prescrip -tion drugs for lowering LDL cholesterol. Unlike their drug counterparts, though, guggulsterones have absolutely no negative side effects.

The cholesterol-reducing effect is important for anyone who's interested in keeping a healthy cardiovascular system—especially those who use steroidal compounds. Anabolic/androgenic steroids increase not only total cholesterol but also the ratio of LDL to HDL.

It's hard to imagine a compound that beneficial having any more benefits, but guggulsterones have also been proven as effective as the drug tetracycline in treating acne. In a 1994 study published in the Journal of Dermatology, 20 patients with nodulocystic acne were randomly given either tetracycline or guggulsterones. Both were taken daily for three months, and both produced a progressive reduction in the lesions in the majority of the patients. Tetracycline reduced them by 65.2 percent, while the guggulsterones produced a 68 percent reduction.

Who can benefit from guggul's effects? Well, who wouldn't like a better complexion? That's especially true for people on anabolic/androgenic steroids, as those drugs tend to increase the skin's oiliness and potential for acne.

competitor. You should take 30 to

Derek Cornelius is a respected bio -chemist and the owner of Syntrax Innovations Inc.

Where else can you find a compound that will help you lose fat, improve your cholesterol profile and at the same time improve your complexion? I've looked long and hard and have yet to find even one competitor. You should take 30 to

60 milligrams three times per day with meals, and always use a product that contains the high-potency, naturally extracted guggul.

Editor's note:

Derek Cornelius is a respected bio -chemist and the owner of Syntrax Innovations Inc.

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Responses

  • john doe
    Derek Cornelius is a worthless hack who believes he the subject of some vast conspiracy spearheaded by bodybuilding.com. Brilliany guy if he could get past the inferiority complex.
    7 years ago

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